Research suggests niacinamide for kidney health could help manage high phosphate levels in advanced kidney disease. The natural form of vitamin B3, also known as nicotinamide, offers hope for improving treatment outcomes.

High phosphate levels, or hyperphosphatemia, affect 72.3% of people undergoing hemodialysis. Elevated phosphate is linked to increased risk of heart disease and overall mortality. Managing these levels is crucial for better health.

Standard treatments include dietary restrictions and phosphate-binding medications. However, success is limited. While 90% of patients on hemodialysis take phosphate binders, only half achieve recommended phosphate levels.

A recent study explored whether adding niacinamide for kidney health could enhance these treatments. Researchers conducted a double-blind trial with participants already using phosphate binders. Over 12 weeks, participants took either a placebo or the supplement, starting at 250 mg daily and increasing to 500 mg.

The results were promising. In the placebo group, phosphate levels continued to rise slightly. In the supplement group, levels dropped significantly. This finding suggests that niacinamide, when combined with phosphate binders, may support lower phosphate levels.

In addition to its potential connection to kidney health, niacinamide is a form of vitamin B3 found in foods such as meat, fish, eggs, and green vegetables. It plays a role in helping the body process fats and sugars and supports healthy cells. The body also converts excess niacin into niacinamide, highlighting its presence in natural metabolic processes.

Finally, the current research opens the door to exploring new possibilities in kidney health management. By studying natural compounds we may uncover additional tools to support those with advanced kidney disease. While more research is needed, these findings inspire hope for future advancements that could improve treatment approaches and overall well-being.